diff --git a/libp2p/host/ping.py b/libp2p/host/ping.py
index 9075f0b..3144ef4 100644
--- a/libp2p/host/ping.py
+++ b/libp2p/host/ping.py
@@ -1,7 +1,7 @@
 import asyncio
 import logging
 
-from libp2p.network.stream.exceptions import StreamEOF, StreamReset
+from libp2p.network.stream.exceptions import StreamClosed, StreamEOF, StreamReset
 from libp2p.network.stream.net_stream_interface import INetStream
 from libp2p.peer.id import ID as PeerID
 from libp2p.typing import TProtocol
@@ -35,7 +35,11 @@ async def _handle_ping(stream: INetStream, peer_id: PeerID) -> bool:
 
     logger.debug("Received ping from %s with data: 0x%s", peer_id, payload.hex())
 
-    await stream.write(payload)
+    try:
+        await stream.write(payload)
+    except StreamClosed:
+        logger.debug("Fail to respond to ping from %s: stream closed", peer_id)
+        raise
     return True
 
 
diff --git a/libp2p/identity/identify/protocol.py b/libp2p/identity/identify/protocol.py
index 87d946c..092deb4 100644
--- a/libp2p/identity/identify/protocol.py
+++ b/libp2p/identity/identify/protocol.py
@@ -3,6 +3,7 @@ import logging
 from multiaddr import Multiaddr
 
 from libp2p.host.host_interface import IHost
+from libp2p.network.stream.exceptions import StreamClosed
 from libp2p.network.stream.net_stream_interface import INetStream
 from libp2p.typing import StreamHandlerFn, TProtocol
 
@@ -43,8 +44,12 @@ def identify_handler_for(host: IHost) -> StreamHandlerFn:
         protobuf = _mk_identify_protobuf(host)
         response = protobuf.SerializeToString()
 
-        await stream.write(response)
-        await stream.close()
-        logger.debug("successfully handled request for %s from %s", ID, peer_id)
+        try:
+            await stream.write(response)
+        except StreamClosed:
+            logger.debug("Fail to respond to %s request: stream closed", ID)
+        else:
+            await stream.close()
+            logger.debug("successfully handled request for %s from %s", ID, peer_id)
 
     return handle_identify
diff --git a/libp2p/pubsub/floodsub.py b/libp2p/pubsub/floodsub.py
index 15ca6b0..bac0bd7 100644
--- a/libp2p/pubsub/floodsub.py
+++ b/libp2p/pubsub/floodsub.py
@@ -1,6 +1,7 @@
 import logging
 from typing import Iterable, List, Sequence
 
+from libp2p.network.stream.exceptions import StreamClosed
 from libp2p.peer.id import ID
 from libp2p.typing import TProtocol
 from libp2p.utils import encode_varint_prefixed
@@ -89,7 +90,10 @@ class FloodSub(IPubsubRouter):
             stream = self.pubsub.peers[peer_id]
             # FIXME: We should add a `WriteMsg` similar to write delimited messages.
             #   Ref: https://github.com/libp2p/go-libp2p-pubsub/blob/master/comm.go#L107
-            await stream.write(encode_varint_prefixed(rpc_msg.SerializeToString()))
+            try:
+                await stream.write(encode_varint_prefixed(rpc_msg.SerializeToString()))
+            except StreamClosed:
+                logger.debug("Fail to publish message to %s: stream closed", peer_id)
 
     async def join(self, topic: str) -> None:
         """
diff --git a/libp2p/pubsub/gossipsub.py b/libp2p/pubsub/gossipsub.py
index 864189e..93faebd 100644
--- a/libp2p/pubsub/gossipsub.py
+++ b/libp2p/pubsub/gossipsub.py
@@ -4,6 +4,7 @@ import logging
 import random
 from typing import Any, Dict, Iterable, List, Sequence, Set
 
+from libp2p.network.stream.exceptions import StreamClosed
 from libp2p.peer.id import ID
 from libp2p.pubsub import floodsub
 from libp2p.typing import TProtocol
@@ -188,7 +189,11 @@ class GossipSub(IPubsubRouter):
             # FIXME: We should add a `WriteMsg` similar to write delimited messages.
             #   Ref: https://github.com/libp2p/go-libp2p-pubsub/blob/master/comm.go#L107
             # TODO: Go use `sendRPC`, which possibly piggybacks gossip/control messages.
-            await stream.write(encode_varint_prefixed(rpc_msg.SerializeToString()))
+            try:
+                await stream.write(encode_varint_prefixed(rpc_msg.SerializeToString()))
+            except StreamClosed:
+                logger.debug("Fail to publish message to %s: stream closed", peer_id)
+                self.pubsub._handle_dead_peer(peer_id)
 
     def _get_peers_to_send(
         self, topic_ids: Iterable[str], msg_forwarder: ID, origin: ID
@@ -512,7 +517,14 @@ class GossipSub(IPubsubRouter):
         peer_stream = self.pubsub.peers[sender_peer_id]
 
         # 4) And write the packet to the stream
-        await peer_stream.write(encode_varint_prefixed(rpc_msg))
+        try:
+            await peer_stream.write(encode_varint_prefixed(rpc_msg))
+        except StreamClosed:
+            logger.debug(
+                "Fail to responed to iwant request from %s: stream closed",
+                sender_peer_id,
+            )
+            self.pubsub._handle_dead_peer(sender_peer_id)
 
     async def handle_graft(
         self, graft_msg: rpc_pb2.ControlGraft, sender_peer_id: ID
@@ -596,4 +608,8 @@ class GossipSub(IPubsubRouter):
         peer_stream = self.pubsub.peers[to_peer]
 
         # Write rpc to stream
-        await peer_stream.write(encode_varint_prefixed(rpc_msg))
+        try:
+            await peer_stream.write(encode_varint_prefixed(rpc_msg))
+        except StreamClosed:
+            logger.debug("Fail to emit control message to %s: stream closed", to_peer)
+            self.pubsub._handle_dead_peer(to_peer)
diff --git a/libp2p/pubsub/pubsub.py b/libp2p/pubsub/pubsub.py
index d5e0267..3834eb4 100644
--- a/libp2p/pubsub/pubsub.py
+++ b/libp2p/pubsub/pubsub.py
@@ -20,7 +20,7 @@ from libp2p.exceptions import ParseError, ValidationError
 from libp2p.host.host_interface import IHost
 from libp2p.io.exceptions import IncompleteReadError
 from libp2p.network.exceptions import SwarmException
-from libp2p.network.stream.exceptions import StreamEOF, StreamReset
+from libp2p.network.stream.exceptions import StreamClosed, StreamEOF, StreamReset
 from libp2p.network.stream.net_stream_interface import INetStream
 from libp2p.peer.id import ID
 from libp2p.typing import TProtocol
@@ -279,13 +279,19 @@ class Pubsub:
 
         # Send hello packet
         hello = self.get_hello_packet()
-        await stream.write(encode_varint_prefixed(hello.SerializeToString()))
+        try:
+            await stream.write(encode_varint_prefixed(hello.SerializeToString()))
+        except StreamClosed:
+            logger.debug("Fail to add new peer %s: stream closed", peer_id)
+            del self.peers[peer_id]
+            return
         # TODO: Check EOF of this stream.
         # TODO: Check if the peer in black list.
         try:
             self.router.add_peer(peer_id, stream.get_protocol())
         except Exception as error:
             logger.debug("fail to add new peer %s, error %s", peer_id, error)
+            del self.peers[peer_id]
             return
 
         logger.debug("added new peer %s", peer_id)
@@ -429,7 +435,12 @@ class Pubsub:
         # Broadcast message
         for stream in self.peers.values():
             # Write message to stream
-            await stream.write(encode_varint_prefixed(raw_msg))
+            try:
+                await stream.write(encode_varint_prefixed(raw_msg))
+            except StreamClosed:
+                peer_id = stream.muxed_conn.peer_id
+                logger.debug("Fail to message peer %s: stream closed", peer_id)
+                self._handle_dead_peer(peer_id)
 
     async def publish(self, topic_id: str, data: bytes) -> None:
         """
diff --git a/setup.py b/setup.py
index 633a10a..27e0f9b 100644
--- a/setup.py
+++ b/setup.py
@@ -58,7 +58,7 @@ setuptools.setup(
     + py_classifiers,
     python_requires=">=3.7,<4",
     install_requires=[
-        "pycryptodome>=3.8.2,<4.0.0",
+        "pycryptodome>=3.9.2,<4.0.0",
         "base58>=1.0.3,<2.0.0",
         "pymultihash>=0.8.2",
         "multiaddr>=0.0.8,<0.1.0",